Anhui Victor Chemical Co., Ltd
Anhui Victor Chemical Co., Ltd
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Name:Calcium 5-methyltetrahydrofolate
CAS#:26560-38-3
Appearance:Off-White to Pale Yellow Solid
Assay:97.0%-102%
Mol.Formula:C20H23CaN7O6
Melting Point: >300°C
Mol.Weight:497.52
| Product Name: | Calcium 5-Methyltetrahydrofolate | Molecular Weight: | 497.52 |
| CAS No: | 26560-38-3 | Molecular Formular: | C20H23CaN7O6 |
| Item | Standard |
| Appearance | White to yellow or beige powder |
| Assay(On dry basis as Ca salt) | 97.0%-102.0% |
| Specific Rotation (C=1.5%in water,25ºC) | +14.5~+18.50 |
| Calcium(Anhydrous basis) | 7.0%-8.5% |
| D-Methylfolate | ≤1.0% |
| Chloride | ≤0.5% |
| Water (K-F) | ≤16.0% |
| Single impurity | ≤1.0% |
| Total impurities | ≤2.5% |
| Residual solvent(Ethanol) | ≤5000ppm |
| Chloride(Cl) | ≤0.5% |
| As | ≤1ppm |
| Heavy Metals | ≤20ppm |
| Boron | ≤20ppm |
| Total plate count | ≤100cuf/g |
| Mold & Yeasts | ≤100cuf/g |
| Salmonella | Negative |
| E. Coil | Negative |
1. mainly for folic acid antagonists (such as methotrexate, pyrimethamine, benzyl cefalexin and trimethoprim) antidote, it's usually used for prevention of methotrexate dose or overdose treatment caused severe toxic effects.
2. folic acid treatment of the following diseases, such as inflammatory diarrhea and protein-energy malnutrition (poor nutrition), pregnancy or infancy megaloblastic anemia caused by poor.
3. as adjuvant therapy for colon cancer, rectal cancer.
4. combined with 5-FU and treatment of digestive tract tumors or other 5-FU-sensitive tumors. High-dose CF used in conjunction with 5-FU (LF), the basic programme is currently the treatment of colon and rectal cancer.
5. for children with leukemia, lymphoma, and osteosarcoma, such as high dose MTX treatment when rescued.
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